Cikotiene, IngaKairys, VisvaldasBuksnaitiene, RitaMorkunas, MariusRudys, SimonasBrukstus, AlgirdasFernandes, Miguel X.2023-02-072023-02-072009Cikotiene, I., Kairys, V., Buksnaitiene, R., Morkunas, M., Rudys, S., Brukstus, A., & Fernandes, M. X. (2009). Study on the cyclization of 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine: microwave versus thermal preparation of pyrido [4, 3-d] pyrimidines. Tetrahedron, 65(29-30), 5752-5759.http://hdl.handle.net/10400.13/5010Thermal and microwave initiated cyclization of 2,4-disubstituted 6-arylethynylpyrimidine-5-carbalde hydes with tert-butylamine has been studied. A novel high-yielding preparation of 2,4-disubstituted 7- arylpyrido[4,3-d]pyrimidines has been developed. The intermediate compounds were isolated and possible mechanism of the reactions is discussed.engCyclizationMicrowave6-Arylethynylpyrimidine-5-carbaldehydesPyrido[4,3-d]pyrimidines1,6-Electrocyclic reaction.Faculdade de Ciências Exatas e da Engenhariajournal article10.1016/j.tet.2009.05.015