Browsing by Author "Brukstus, Algirdas"
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- Study on the cyclization of 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine: microwave versus thermal preparation of pyrido[4,3-d]pyrimidinesPublication . Cikotiene, Inga; Kairys, Visvaldas; Buksnaitiene, Rita; Morkunas, Marius; Rudys, Simonas; Brukstus, Algirdas; Fernandes, Miguel X.Thermal and microwave initiated cyclization of 2,4-disubstituted 6-arylethynylpyrimidine-5-carbalde hydes with tert-butylamine has been studied. A novel high-yielding preparation of 2,4-disubstituted 7- arylpyrido[4,3-d]pyrimidines has been developed. The intermediate compounds were isolated and possible mechanism of the reactions is discussed.