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Objectively measured time spent sedentary is associated with insulin resistance independent of overall and central body fat in 9-to 10-year-old portuguese children
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Advisor(s)
Abstract(s)
OBJECTIVE — We examined the independent relationships between objectively measured
physical activity and insulin resistance in Portuguese children.
RESEARCH DESIGN AND METHODS — This is a school-based, cross-sectional study
in 147 randomly selected girls (aged 9.8 0.3 years; 27.8 9.3% body fat) and 161 boys (aged
9.8 0.3 years; 22.0 9.2% body fat). Physical activity was assessed by the Actigraph accel erometer for 4 days and summarized as time spent sedentary (accelerometer counts 500/min),
in light-intensity (accelerometer counts 500–2,000/min), and in moderate- and vigorous intensity activity (accelerometer counts 2,001/min). We measured total and central fat mass by
dual-energy X-ray absorptiometry. Insulin resistance was expressed as the homeostasis model
assessment score.
RESULTS — Time (min/day) spent sedentary was significantly and positively associated with
insulin resistance ( -coefficient 0.001 [95% CI 0.0002–0.002]; P 0.013). Time spent in
moderate- and vigorous-intensity physical activity ( 0.002 [ 0.003 to 0.001]; P 0.0009)
and overall physical activity ( 0.001 [ 0.008 to 0.003]; P 0.0001) were significantly and
inversely associated with insulin resistance. All associations remained statistically significant,
although they were attenuated after further adjustments for sex, birth weight, sexual maturity,
and total or central fat mass (P 0.03).
CONCLUSIONS — Physical activity is associated with insulin resistance independent of
total and central fat mass in children. Our results emphasize the importance of decreasing
sedentary behavior and increasing time spent in moderate- and vigorous-intensity activity in
children, which may have beneficial effects on metabolic risk factors regardless of the degree of
adiposity.
Description
Keywords
Insulin resistance Physical activity Sedentary Central body fat Portuguese children . Faculdade de Ciências Sociais
Citation
Sardinha, L. B., Andersen, L. B., Anderssen, S. A., Quitério, A. L., Ornelas, R., Froberg, K., ... & Ekelund, U. (2008). Objectively measured time spent sedentary is associated with insulin resistance independent of overall and central body fat in 9-to 10-year-old portuguese children. Diabetes care, 31(3), 569-575. https://doi.org/10.2337/dc07-1286
Publisher
American Diabetes Association