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Characterization of phenolic compounds in Helichrysum melaleucumby high-performance liquid chromatography with on-line ultraviolet and mass spectrometry detection

2010Journal article Open access
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dc.contributor.authorGouveia, Sandra C.
dc.contributor.authorCastilho, Paula C.
dc.date.accessioned2021-04-08T12:58:20Z
dc.date.available2021-04-08T12:58:20Z
dc.date.issued2010
dc.description.abstractHelicrysum melaleucum is a medicinal plant traditionally used in the islands of the Macaronesia region for the treatment of respiratory diseases. In this work, the phenolic compounds of Helicrysum melaleucum plants collected in different geographical locations of Madeira Island and their morphological parts (total aerial parts, leaves, flowers and stems) were extracted and analyzed separately by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC-DAD/ESI-MS(n)). A total of 68 compounds were characterized based mainly on their UV and mass spectra. These included derivatives of O-glycosylated flavonoids (flavonol and flavones type), quinic acid, caffeic acid, lignans and polyphenols. The flowers were found to be the morphological part with higher variety of phenolic compounds. The large differences in the phenolic composition of plants collected from different geographical locations allowed the identification of a few components, such as pinoresinol and methoxylated flavone derivatives, likely to be useful as geographical markers. Also, these results promote further comparison of the bioactivities of the different samples analyzed. This paper marks the first report on the chemical analysis of Helichrysum melaleucum species.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGouveia, S. C., & Castilho, P. C. (2010). Characterization of phenolic compounds in Helichrysum melaleucum by high‐performance liquid chromatography with on‐line ultraviolet and mass spectrometry detection. Rapid Communications in Mass Spectrometry, 24(13), 1851-1868.pt_PT
dc.identifier.doi10.1002/rcm.4585pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/3259
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relationISOLAMENTO E CARACTERIZAÇÃO DE PRINCÍPIOS ACTIVOS DE PLANTAS PARA O COMBATE À TUBERCULOSE
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectHelichrysum melaleucumpt_PT
dc.subjectPhenolic compoundspt_PT
dc.subjectHigh-performance liquid chromatographypt_PT
dc.subjectElectrospray ionizationpt_PT
dc.subjectMass spectrometry detectionpt_PT
dc.subjectUltraviolet detectionpt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.titleCharacterization of phenolic compounds in Helichrysum melaleucumby high-performance liquid chromatography with on-line ultraviolet and mass spectrometry detectionpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleISOLAMENTO E CARACTERIZAÇÃO DE PRINCÍPIOS ACTIVOS DE PLANTAS PARA O COMBATE À TUBERCULOSE
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F24227%2F2005/PT
oaire.citation.endPage1868pt_PT
oaire.citation.issue13pt_PT
oaire.citation.startPage1851pt_PT
oaire.citation.titleRapid Communications in Mass Spectrometrypt_PT
oaire.citation.volume24pt_PT
person.familyNameGouveia-Figueira
person.familyNameCastilho
person.givenNameSandra
person.givenNamePaula C
person.identifierA-4412-2013
person.identifier.ciencia-id6D15-8C69-A2E0
person.identifier.orcid0000-0002-8116-2794
person.identifier.orcid0000-0002-8303-4286
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublicationd84fd917-438e-43bf-ac6f-256562481c05
relation.isAuthorOfPublication.latestForDiscoveryd84fd917-438e-43bf-ac6f-256562481c05
relation.isProjectOfPublicatione32bdc44-7898-4a45-be04-7048bfb66579
relation.isProjectOfPublication.latestForDiscoverye32bdc44-7898-4a45-be04-7048bfb66579

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