Publication
Changes in the phenolic compositions of Elaeagnus umbellata and Sambucus lanceolata after in vitro gastrointestinal digestion and evaluation of their potential anti-diabetic properties
dc.contributor.author | Spínola, Vítor | |
dc.contributor.author | Pinto, Joana | |
dc.contributor.author | Llorent-Martínez, Eulogio J. | |
dc.contributor.author | Castilho, Paula C. | |
dc.date.accessioned | 2021-03-25T09:57:27Z | |
dc.date.available | 2021-03-25T09:57:27Z | |
dc.date.issued | 2019 | |
dc.description.abstract | In this work, the phenolic composition of E. umbellata leaves and berries is reported. Berries were rich in flavonols, whereas leaves presented abundant flavonols and ellagitannins. Then, the enzyme-inhibitory properties, anti-glycation and antioxidant activities of E. umbellata and Sambucus lanceolata (its phenolic profile has been already established in a previous work) were tested by several in vitro assays and compared. The simulated gastrointestinal digestion resulted in a decrease on their phenolic composition. Nevertheless, both species still had the ability to inhibit aldose reductase activity and protein glycation and scavenge free radicals at the end of the process. Thus, the potential beneficial effects of E. umbellata and S. lanceolata seems to be kept to some extent after passage throughout the digestive system. Altogether, this study provides further insight into investigation of these species as dietary sources of bioactive compounds to lower the risk of type-2 diabetes and obesity. | pt_PT |
dc.description.sponsorship | The authors are grateful to Esmeralda Dias from “A Quintinha das Aromáticas” (Funchal, Portugal) for the supply of E. umbellata samples and to Francisco Fernandes and José Carvalho from Madeira Botanical Garden (Funchal) for the identification of plant material. V. Spínola acknowledges Fundação para a Ciência e a Tecnologia (FCT, Portugal) for a Ph.D. grant SFRH/BD/84672/2012. This work was also supported by FCT (project PEst-OE/QUI/UI0674/2019, CQM, Portuguese Government funds) and the Portuguese National Mass Spectrometry Network (Contract RNEMREDE/1508/REM/2005), and through Madeira 14-20 Program, project PROEQUIPRAM - Reforço do Investimento em Equipamentos e Infraestruturas Científicas na RAM (M1420-01-0145-FEDER-000008) and by ARDITI-Agência Regional para o Desenvolvimento da Investigação Tecnologia e Inovação, through the project M1420-01-0145-FEDER-000005 - Centro de Química da Madeira - CQM+ (Madeira 14-20). | pt_PT |
dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
dc.identifier.citation | Spínola, V., Pinto, J., Llorent-Martínez, E. J., & Castilho, P. C. (2019). Changes in the phenolic compositions of Elaeagnus umbellata and Sambucus lanceolata after in vitro gastrointestinal digestion and evaluation of their potential anti-diabetic properties. Food Research International, 122, 283-294. 10.1016/j.foodres.2019.04.030 | pt_PT |
dc.identifier.doi | 10.1016/j.foodres.2019.04.030 | pt_PT |
dc.identifier.uri | http://hdl.handle.net/10400.13/3199 | |
dc.language.iso | eng | pt_PT |
dc.peerreviewed | yes | pt_PT |
dc.publisher | Canadian Institute of Food Science and Technology (CIFST) | pt_PT |
dc.relation | Strategic Project - UI 674 - 2014 | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
dc.subject | Elaeagnus umbellata | pt_PT |
dc.subject | Sambucus lanceolata | pt_PT |
dc.subject | Phenolic composition | pt_PT |
dc.subject | Gastrointestinal digestion simulation | pt_PT |
dc.subject | Digestive enzymes inhibition | pt_PT |
dc.subject | Aldose reductase | pt_PT |
dc.subject | Protein glycation | pt_PT |
dc.subject | Antioxidant activity | pt_PT |
dc.subject | . | pt_PT |
dc.subject | Faculdade de Ciências Exatas e da Engenharia | pt_PT |
dc.subject | Centro de Química da Madeira | |
dc.title | Changes in the phenolic compositions of Elaeagnus umbellata and Sambucus lanceolata after in vitro gastrointestinal digestion and evaluation of their potential anti-diabetic properties | pt_PT |
dc.type | journal article | |
dspace.entity.type | Publication | |
oaire.awardTitle | Strategic Project - UI 674 - 2014 | |
oaire.awardURI | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F84672%2F2012/PT | |
oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FQUI%2FUI0674%2F2014/PT | |
oaire.citation.endPage | 294 | pt_PT |
oaire.citation.startPage | 283 | pt_PT |
oaire.citation.title | Food Research International | pt_PT |
oaire.citation.volume | 122 | pt_PT |
oaire.fundingStream | SFRH | |
oaire.fundingStream | 6817 - DCRRNI ID | |
person.familyName | Spínola | |
person.familyName | Nunes Pinto | |
person.familyName | Castilho | |
person.givenName | Vítor | |
person.givenName | Joana Carolina | |
person.givenName | Paula C | |
person.identifier | A-4412-2013 | |
person.identifier.ciencia-id | 0412-6D53-3A09 | |
person.identifier.ciencia-id | 6D15-8C69-A2E0 | |
person.identifier.orcid | 0000-0003-2456-8613 | |
person.identifier.orcid | 0000-0002-8303-4286 | |
person.identifier.scopus-author-id | 54881258000 | |
project.funder.identifier | http://doi.org/10.13039/501100001871 | |
project.funder.identifier | http://doi.org/10.13039/501100001871 | |
project.funder.name | Fundação para a Ciência e a Tecnologia | |
project.funder.name | Fundação para a Ciência e a Tecnologia | |
rcaap.rights | openAccess | pt_PT |
rcaap.type | article | pt_PT |
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relation.isProjectOfPublication.latestForDiscovery | 34751b34-607a-473a-bc2e-ffc6b725cf18 |
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