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Underlying features of prostate cancer—Statistics, risk factors, and emerging methods for Its diagnosis

datacite.subject.fosCiências Médicas::Biotecnologia Médica
datacite.subject.fosCiências Médicas::Medicina Clínica
dc.contributor.authorBerenguer, Cristina V.
dc.contributor.authorPereira, Ferdinando
dc.contributor.authorCâmara, José S.
dc.contributor.authorPereira, Jorge A. M.
dc.contributor.authorBerenguer, Cristina
dc.contributor.authorCâmara, José
dc.contributor.authorAugusto Machado Pereira, Jorge
dc.date.accessioned2025-06-16T13:31:41Z
dc.date.available2025-06-16T13:31:41Z
dc.date.issued2023-02-15
dc.description.abstract<jats:p>Prostate cancer (PCa) is the most frequently occurring type of malignant tumor and a leading cause of oncological death in men. PCa is very heterogeneous in terms of grade, phenotypes, and genetics, displaying complex features. This tumor often has indolent growth, not compromising the patient’s quality of life, while its more aggressive forms can manifest rapid growth with progression to adjacent organs and spread to lymph nodes and bones. Nevertheless, the overtreatment of PCa patients leads to important physical, mental, and economic burdens, which can be avoided with careful monitoring. Early detection, even in the cases of locally advanced and metastatic tumors, provides a higher chance of cure, and patients can thus go through less aggressive treatments with fewer side effects. Furthermore, it is important to offer knowledge about how modifiable risk factors can be an effective method for reducing cancer risk. Innovations in PCa diagnostics and therapy are still required to overcome some of the limitations of the current screening techniques, in terms of specificity and sensitivity. In this context, this review provides a brief overview of PCa statistics, reporting its incidence and mortality rates worldwide, risk factors, and emerging screening strategies.</jats:p>eng
dc.identifier.citationBerenguer, C.V.; Pereira, F.; Câmara, J.S.; Pereira, J.A.M. Underlying Features of Prostate Cancer—Statistics, Risk Factors, and Emerging Methods for Its Diagnosis. Curr. Oncol. 2023, 30, 2300–2321. https://doi.org/10.3390/ curroncol30020178
dc.identifier.doi10.3390/curroncol30020178
dc.identifier.issn1718-7729
dc.identifier.urihttp://hdl.handle.net/10400.13/7308
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relationMadeira Chemistry Research Centre
dc.relationMadeira Chemistry Research Centre
dc.relation.ispartofCurrent Oncology
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectProstate cancer
dc.subjectIncidence
dc.subjectMortality
dc.subjectRisk factors
dc.subjectBiomarkers
dc.subject.
dc.subjectCentro de Química da Madeira
dc.subjectFaculdade de Ciências Exatas e da Engenharia
dc.titleUnderlying features of prostate cancer—Statistics, risk factors, and emerging methods for Its diagnosiseng
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMadeira Chemistry Research Centre
oaire.awardTitleMadeira Chemistry Research Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00674%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00674%2F2020/PT
oaire.citation.issue2
oaire.citation.titleCurrent Oncology
oaire.citation.volume30
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameBerenguer
person.familyNameCâmara
person.familyNameAugusto Machado Pereira
person.givenNameCristina
person.givenNameJosé
person.givenNameJorge
person.identifierG-3003-2013
person.identifier.ciencia-idA813-68FE-C3C3
person.identifier.ciencia-id481C-08CE-90E5
person.identifier.ciencia-idEC12-EE8F-50E8
person.identifier.orcid0000-0002-1762-1175
person.identifier.orcid0000-0003-1965-3151
person.identifier.orcid0000-0003-0316-5348
person.identifier.scopus-author-id10140393000
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
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