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Unravelling the potential of salivary volatile metabolites in oral diseases. A review

2020Journal article Open access
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dc.contributor.authorPereira, Jorge A. M.
dc.contributor.authorPorto-Figueira, Priscilla
dc.contributor.authorTaware, Ravindra
dc.contributor.authorSukul, Pritam
dc.contributor.authorRapole, Srikanth
dc.contributor.authorCâmara, José S.
dc.date.accessioned2021-11-30T08:42:29Z
dc.date.available2021-11-30T08:42:29Z
dc.date.issued2020
dc.description.abstractFostered by the advances in the instrumental and analytical fields, in recent years the analysis of volatile organic compounds (VOCs) has emerged as a new frontier in medical diagnostics. VOCs analysis is a non-invasive, rapid and inexpensive strategy with promising potential in clinical diagnostic procedures. Since cellular metabolism is altered by diseases, the resulting metabolic effects on VOCs may serve as biomarkers for any given pathophysiologic condition. Human VOCs are released from biomatrices such as saliva, urine, skin emanations and exhaled breath and are derived from many metabolic pathways. In this review, the potential of VOCs present in saliva will be explored as a monitoring tool for several oral diseases, including gingivitis and periodontal disease, dental caries, and oral cancer. Moreover, the analytical state-of-the-art for salivary volatomics, e.g., the most common extraction techniques along with the current challenges and future perspectives will be addressed unequivocallypt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPereira, J. A., Porto-Figueira, P., Taware, R., Sukul, P., Rapole, S., & Câmara, J. S. (2020). Unravelling the potential of salivary volatile metabolites in oral diseases. A review. Molecules, 25(13), 3098. https://doi.org/10.3390/molecules25133098pt_PT
dc.identifier.doi10.3390/molecules25133098pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/3869
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationMadeira Chemistry Research Centre
dc.relationMadeira Chemistry Research Centre
dc.relationHNC-i3OMICS - Development of an innovative and integrated platform based on OMICS patterns towards the next generation of cancer diagnosis and management
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectSalivapt_PT
dc.subjectVolatile organic compounds (VOCs)pt_PT
dc.subjectOral diseases (ODs);pt_PT
dc.subjectBiomarkerspt_PT
dc.subjectAnalytical platformspt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.subjectCentro de Química da Madeira
dc.titleUnravelling the potential of salivary volatile metabolites in oral diseases. A reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMadeira Chemistry Research Centre
oaire.awardTitleMadeira Chemistry Research Centre
oaire.awardTitleHNC-i3OMICS - Development of an innovative and integrated platform based on OMICS patterns towards the next generation of cancer diagnosis and management
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00674%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00674%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/OE/SFRH%2FBD%2F129630%2F2017/PT
oaire.citation.issue13pt_PT
oaire.citation.startPage3098pt_PT
oaire.citation.titleMoleculespt_PT
oaire.citation.volume25pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamOE
person.familyNameAugusto Machado Pereira
person.familyNamePorto-Figueira
person.familyNameTaware
person.familyNameCâmara
person.givenNameJorge
person.givenNamePriscilla
person.givenNameRavindra
person.givenNameJosé
person.identifierG-3003-2013
person.identifier.ciencia-idEC12-EE8F-50E8
person.identifier.ciencia-idAD11-4860-FB1B
person.identifier.ciencia-id481C-08CE-90E5
person.identifier.orcid0000-0003-0316-5348
person.identifier.orcid0000-0001-7773-182X
person.identifier.orcid0000-0001-7893-2850
person.identifier.orcid0000-0003-1965-3151
person.identifier.scopus-author-id56724173300
person.identifier.scopus-author-id57195429801
person.identifier.scopus-author-id10140393000
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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