Repository logo
 
Publication

Breast cancer metabolomics: from analytical platforms to multivariate data analysis. A review

2019Journal article Open access
Simple item page
dc.contributor.authorSilva, Catarina
dc.contributor.authorPerestrelo, Rosa
dc.contributor.authorSilva, Pedro
dc.contributor.authorTomás, Helena
dc.contributor.authorCâmara, José S.
dc.date.accessioned2020-07-09T10:43:27Z
dc.date.available2020-07-09T10:43:27Z
dc.date.issued2019
dc.description.abstractCancer is a major health issue worldwide for many years and has been increasing significantly. Among the different types of cancer, breast cancer (BC) remains the leading cause of cancer-related deaths in women being a disease caused by a combination of genetic and environmental factors. Nowadays, the available diagnostic tools have aided in the early detection of BC leading to the improvement of survival rates. However, better detection tools for diagnosis and disease monitoring are still required. In this sense, metabolomic NMR, LC-MS and GC-MS-based approaches have gained attention in this field constituting powerful tools for the identification of potential biomarkers in a variety of clinical fields. In this review we will present the current analytical platforms and their applications to identify metabolites with potential for BC biomarkers based on the main advantages and advances in metabolomics research. Additionally, chemometric methods used in metabolomics will be highlighted.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSilva, C.; Perestrelo, R.; Silva, P.; Tomás, H.; Câmara, J.S. Breast cancer metabolomics: from analytical platforms to multivariate data analysis. A Review. Metabolites 2019, 9, 102.pt_PT
dc.identifier.doi10.3390/metabo9050102pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/2843
dc.language.isoengpt_PT
dc.publisherMDPIpt_PT
dc.relationStrategic Project - UI 674 - 2014
dc.relationEXPLORING THE VOLATOME OF NONCOMMUNICABLE DISEASES AS A PROMISING, INNOVATIVE AND INTEGRATING APPROACH FOR THEIR RAPID DIAGNOSTICS. THE CASE STUDY OF CANCER AND NEURODEGENERATIVE DISEASES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBreast cancerpt_PT
dc.subjectOmicspt_PT
dc.subjectAnalytical platformspt_PT
dc.subjectChemometric methodspt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.subjectCentro de Química da Madeira
dc.titleBreast cancer metabolomics: from analytical platforms to multivariate data analysis. A reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 674 - 2014
oaire.awardTitleEXPLORING THE VOLATOME OF NONCOMMUNICABLE DISEASES AS A PROMISING, INNOVATIVE AND INTEGRATING APPROACH FOR THEIR RAPID DIAGNOSTICS. THE CASE STUDY OF CANCER AND NEURODEGENERATIVE DISEASES
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FQUI%2FUI0674%2F2014/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/Inn-INDIGO%2F0001%2F2015/PT
oaire.citation.endPage31pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleMetabolitespt_PT
oaire.citation.volume9pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream3599-PPCDT
person.familyNameSousa Luís
person.familyNamePerestrelo
person.familyNameTomás
person.familyNameCâmara
person.givenNameCatarina Grace
person.givenNameRosa
person.givenNameHelena
person.givenNameJosé
person.identifierC-1300-2019
person.identifier1441319
person.identifier556975
person.identifierG-3003-2013
person.identifier.ciencia-id9813-3B88-BA8D
person.identifier.ciencia-id251A-D5F7-9E32
person.identifier.ciencia-id4D14-D31E-A8BE
person.identifier.ciencia-id481C-08CE-90E5
person.identifier.orcid0000-0002-3018-3165
person.identifier.orcid0000-0002-7223-1022
person.identifier.orcid0000-0002-7856-2041
person.identifier.orcid0000-0003-1965-3151
person.identifier.ridI-2307-2014
person.identifier.ridE-5991-2010
person.identifier.scopus-author-id57194492726
person.identifier.scopus-author-id16686828800
person.identifier.scopus-author-id6508104177
person.identifier.scopus-author-id10140393000
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication2853e6b6-0fb5-454c-aedb-05528b76c484
relation.isAuthorOfPublication003ff241-47d2-497b-b9ac-c0d1713f8bf3
relation.isAuthorOfPublication3a747114-6ab9-454b-985b-00cbf792e273
relation.isAuthorOfPublicatione10d78be-e547-4d25-92b5-06a997ed78da
relation.isAuthorOfPublication.latestForDiscovery3a747114-6ab9-454b-985b-00cbf792e273
relation.isProjectOfPublication75aaadc4-cd17-4fec-ba9d-1d0e564b3731
relation.isProjectOfPublication31fd4a52-8b42-4c58-95a2-b4644fe10d9f
relation.isProjectOfPublication.latestForDiscovery75aaadc4-cd17-4fec-ba9d-1d0e564b3731

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Breast Cancer Metabolomics From Analytical Platforms to Multivariate Data Analysis. A ReviewJoséCâmara._.pdf
Size:
1.82 MB
Format:
Adobe Portable Document Format
Download

Collections

Artigos em revistas internacionais