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Y-chromosome lineages in Cabo Verde Islands witness the diverse geographic origin of its first male settlers

2003Journal article Open access
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dc.contributor.authorGonçalves, Rita
dc.contributor.authorRosa, Alexandra
dc.contributor.authorFreitas, Ana
dc.contributor.authorFernandes, Ana
dc.contributor.authorKivisild, Toomas
dc.contributor.authorVillems, Richard
dc.contributor.authorBrehm, António
dc.date.accessioned2020-12-29T11:47:52Z
dc.date.available2020-12-29T11:47:52Z
dc.date.issued2003
dc.description.abstractThe Y-chromosome haplogroup composition of the population of the Cabo Verde Archipelago was profiled by using 32 single-nucleotide polymorphism markers and compared with potential source populations from Iberia, west Africa, and the Middle East. According to the traditional view, the major proportion of the founding population of Cabo Verde was of west African ancestry with the addition of a minor fraction of male colonizers from Europe. Unexpectedly, more than half of the paternal lineages (53.5%) of Cabo Verdeans clustered in haplogroups I, J, K, and R1, which are characteristic of populations of Europe and the Middle East, while being absent in the probable west African source population of Guiné-Bissau. Moreover, a high frequency of J* lineages in Cabo Verdeans relates them more closely to populations of the Middle East and probably provides the first genetic evidence of the legacy of the Jews. In addition, the considerable proportion (20.5%) of E3b(xM81) lineages indicates a possible gene flow from the Middle East or northeast Africa, which, at least partly, could be ascribed to the Sephardic Jews. In contrast to the predominance of west African mitochondrial DNA haplotypes in their maternal gene pool, the major west African Y-chromosome lineage E3a was observed only at a frequency of 15.9%. Overall, these results indicate that gene flow from multiple sources and various sex-specific patterns have been important in the formation of the genomic diversity in the Cabo Verde islands.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGonçalves, R., Rosa, A., Freitas, A., Fernandes, A., Kivisild, T., Villems, R., & Brehm, A. (2003). Y-chromosome lineages in Cabo Verde Islands witness the diverse geographic origin of its first male settlers. Human genetics, 113(6), 467-472.pt_PT
dc.identifier.doi10.1007/s00439-003-1007-4pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/3047
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.relationPOLIMORFISMOS GENÉTICOS E RISCO DE DOENÇA CORONÁRIA NA MADEIRA. INTERACÇÃO COM OS MARCADORES DE RISCO CARDIOVASCULAR E O SEU PAPEL NO PROGNÓSTICO
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectHaplotypespt_PT
dc.subjectCabo Verdept_PT
dc.subjectMalept_PT
dc.subjectPhylogenypt_PT
dc.subjectPolymorphism, Single Nucleotidept_PT
dc.subjectChromosomes, Human, Ypt_PT
dc.subjectEmigration and Immigrationpt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências da Vidapt_PT
dc.titleY-chromosome lineages in Cabo Verde Islands witness the diverse geographic origin of its first male settlerspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitlePOLIMORFISMOS GENÉTICOS E RISCO DE DOENÇA CORONÁRIA NA MADEIRA. INTERACÇÃO COM OS MARCADORES DE RISCO CARDIOVASCULAR E O SEU PAPEL NO PROGNÓSTICO
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POCI-2010/SFRH%2FBD%2F8592%2F2002/PT
oaire.citation.endPage472pt_PT
oaire.citation.startPage467pt_PT
oaire.citation.titleHuman Geneticspt_PT
oaire.citation.volume113(6)pt_PT
oaire.fundingStreamPOCI-2010
person.familyNameGonçalves
person.familyNameda Silva Rosa
person.familyNameBrehm
person.givenNameRita
person.givenNamePatrícia Alexandra
person.givenNameAntonio
person.identifier.ciencia-id8F1B-4B72-4E80
person.identifier.ciencia-idF01B-3B5B-2269
person.identifier.ciencia-id3613-8D1F-0EDF
person.identifier.orcid0000-0002-5306-2032
person.identifier.orcid0000-0002-1827-6828
person.identifier.orcid0000-0003-3168-5340
person.identifier.scopus-author-idAuthor ID 7006085833
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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