Repository logo
 
Publication

Distribution of HLA alleles in Portugal and Cabo Verde. Relationships with the slave trade route

2002Journal article Restricted access
Simple item page
dc.contributor.authorSpínola, Hélder
dc.contributor.authorBrehm, A.
dc.contributor.authorWilliams, F.
dc.contributor.authorJesus, J.
dc.contributor.authorMiddleton, D.
dc.date.accessioned2018-11-09T14:22:32Z
dc.date.available2018-11-09T14:22:32Z
dc.date.issued2002
dc.description.abstractHLA-A,-B, and -DR frequencies were analysed in populations from Portugal and the Madeira and Cabo Verde Archipelagos, aiming to characterize their genetic composition. Portuguese settlers colonized both Archipelagos in the 15th and 16th centuries. Madeira received many sub-Saharan slaves to work in the sugar plantations, and Cabo Verde served as a pivotal market in the Atlantic slave trade and was populated by individuals coming from the Senegambia region of the West African coast. The population of Madeira shows the highest genetic diversity and the presence of alleles and haplotypes usually linked to sub-Saharan populations, the haplotypes accounting for 3±5% of the total. Cabo Verde presents typical markers acknowledged to be of European or IberoMediterranean origin, thus revealing the admixture of European settlers with Sub-Saharan slaves. Altogether the number of European haplotypes reaches 15% of the total. The Portuguese population shows a perceivable and significant heterogeneity both in allele and haplotype frequencies, unveiling a differential input of peoples from different origins. A PCA of the populations studied, plus other relevant ones, clearly shows gene heterogeneity in mainland Portugal as well as the differences and relationships between these populations and Madeira and Cabo Verde.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSpínola, H., Brehm, A., Williams, F., Jesús, J., & Middleton, D. (2002). Distribution of HLA alleles in Portugal and Cabo Verde. Relationships with the slave trade route. Annals of human genetics, 66(4), 285-296.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/2148
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherUniversity College Londonpt_PT
dc.subjectHLA allelespt_PT
dc.subjectSlave trade routept_PT
dc.subjectPortugalpt_PT
dc.subjectCabo Verdept_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências da Vidapt_PT
dc.titleDistribution of HLA alleles in Portugal and Cabo Verde. Relationships with the slave trade routept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceLondonpt_PT
oaire.citation.endPage296pt_PT
oaire.citation.startPage285pt_PT
oaire.citation.titleAnnals of Human Geneticspt_PT
oaire.citation.volume66(4)pt_PT
person.familyNameSpínola
person.familyNameBrehm
person.familyNameAbreu de Jesus
person.givenNameHélder
person.givenNameAntonio
person.givenNameJosé Manuel
person.identifier293002
person.identifier.ciencia-id3613-8D1F-0EDF
person.identifier.ciencia-id7511-B0D4-B350
person.identifier.orcid0000-0002-6455-1595
person.identifier.orcid0000-0003-3168-5340
person.identifier.orcid0000-0001-8509-2757
person.identifier.scopus-author-id10242534600
person.identifier.scopus-author-idAuthor ID 7006085833
person.identifier.scopus-author-id6701828369
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication1ba0f1f6-73c8-46b2-b152-8cd3c90207ed
relation.isAuthorOfPublication62d279e2-247a-4652-a370-3e8c2a846e31
relation.isAuthorOfPublicationa6be2afd-2cd9-420b-b08b-5fe354545ac1
relation.isAuthorOfPublication.latestForDiscovery62d279e2-247a-4652-a370-3e8c2a846e31

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Distribution of HLA alleles in Portugal and Cabo Verde. Relationships with the slave trade route.pdf
Size:
261.63 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artigos em revistas internacionais