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Carbon nanotube-incorporated multilayered cellulose acetate nanofibers for tissue engineering applications

2013Journal article Restricted access
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dc.contributor.authorLuo, Yu
dc.contributor.authorWang, Shige
dc.contributor.authorShen, Mingwu
dc.contributor.authorQi, Ruiling
dc.contributor.authorFang, Yi
dc.contributor.authorGuo, Rui
dc.contributor.authorCai, Hongdong
dc.contributor.authorCao, Xueyan
dc.contributor.authorTomás, Helena
dc.contributor.authorZhu, Meifang
dc.contributor.authorShi, Xiangyang
dc.date.accessioned2019-07-09T14:44:33Z
dc.date.available2019-07-09T14:44:33Z
dc.date.issued2013
dc.description.abstractWe report the fabrication of a novel carbon nanotube-containing nanofibrous polysaccharide scaffolding material via the combination of electrospinning and layer-by-layer (LbL) self-assembly techniques for tissue engineering applications. In this approach, electrospun cellulose acetate (CA) nanofibers were assembled with positively charged chitosan (CS) and negatively charged multiwalled carbon nanotubes (MWCNTs) or sodium alginate (ALG) via a LbL technique. We show that the 3-dimensional fibrous structures of the CA nanofibers do not appreciably change after the multilayered assembly process except that the surface of the fibers became much rougher than that before assembly. The incorporation of MWCNTs in the multilayered CA fibrous scaffolds tends to endow the fibers with improved mechanical property and promote fibroblast attachment, spreading, and proliferation when compared with CS/ALG multilayer-assembled fibrous scaffolds. The approach to engineering the nanofiber surfaces via LbL assembly likely provides many opportunities for new scaffolding materials design in various tissue engineering applications.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationLuo, Y., Wang, S., Shen, M., Qi, R., Fang, Y., Guo, R., ... & Shi, X. (2013). Carbon nanotube-incorporated multilayered cellulose acetate nanofibers for tissue engineering applications. Carbohydrate polymers, 91(1), 419-427.pt_PT
dc.identifier.doi10.1016/j.carbpol.2012.08.069pt_PT
dc.identifier.issn0144-8617
dc.identifier.urihttp://hdl.handle.net/10400.13/2469
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationStrategic Project - UI 674 - 2011-2012
dc.subjectSelf-assemblypt_PT
dc.subjectCarbon nanotubept_PT
dc.subjectElectrospinningpt_PT
dc.subjectNanofiberpt_PT
dc.subjectCell culturept_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.subjectCentro de Química da Madeira
dc.titleCarbon nanotube-incorporated multilayered cellulose acetate nanofibers for tissue engineering applicationspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 674 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FQUI%2FUI0674%2F2011/PT
oaire.citation.endPage427pt_PT
oaire.citation.startPage419pt_PT
oaire.citation.titleCarbohydrate Polymerspt_PT
oaire.citation.volume91(1)pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameWang
person.familyNameCao
person.familyNameTomás
person.familyNameShi
person.givenNameShige
person.givenNameXueyan
person.givenNameHelena
person.givenNameXiangyang
person.identifier556975
person.identifier.ciencia-id4D14-D31E-A8BE
person.identifier.ciencia-idBA11-1437-B948
person.identifier.orcid0000-0002-7639-6035
person.identifier.orcid0000-0003-4366-8943
person.identifier.orcid0000-0002-7856-2041
person.identifier.orcid0000-0001-6785-6645
person.identifier.ridE-5991-2010
person.identifier.ridA-1289-2007
person.identifier.scopus-author-id53882129600
person.identifier.scopus-author-id6508104177
person.identifier.scopus-author-id7402953116
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication3a747114-6ab9-454b-985b-00cbf792e273
relation.isAuthorOfPublicationc6b4b8c5-1241-4906-b4b9-ace5576b0b62
relation.isAuthorOfPublication.latestForDiscovery99549723-d322-4722-bbab-84d5f445cd81
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