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Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems

2020Journal article Open access
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dc.contributor.authorOlim, Filipe
dc.contributor.authorNeves, Ana Rute
dc.contributor.authorWang, Zhao
dc.contributor.authorSun, Jingjing
dc.contributor.authorTomás, Helena
dc.contributor.authorSheng, Ruilong
dc.date.accessioned2021-11-16T14:22:44Z
dc.date.available2021-11-16T14:22:44Z
dc.date.issued2020
dc.description.abstractUsing natural lipids to covalently connect with antitumor agents to construct lipid-based molecular prodrugs and their nanosystems is a promising research frontier for sustainable medicinal chemistry, nanobiotechnology and tumor chemotherapy. This paper reviewed recent progress of lipid-based doxorubicin (molecular) prodrugs and their nanodelivery systems, including lipid-doxorubicin prodrugs, stimuli-responsive lipid-doxorubicin prodrugs, and lipid-doxorubicin prodrug-based drug co-delivery nanosystems. Additionally, possible future research outlooks in this field were also discussed.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationOlim, F., Neves, A. R., Wang, Z., Sun, J., Tomás, H., & Sheng, R. (2020). Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems. Medicine Research, 4(1-2), 200013. DOI: 10.21127/yaoyimr20200013pt_PT
dc.identifier.doi10.21127/yaoyimr20200013pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/3820
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMedicine Researchpt_PT
dc.relationMadeira Chemistry Research Centre
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectLipidpt_PT
dc.subjectDoxorubicinpt_PT
dc.subjectProdrugspt_PT
dc.subjectStimuli-responsivept_PT
dc.subjectDrug co-deliverypt_PT
dc.subjectNanosystemspt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.subjectCentro de Química da Madeira
dc.titleProdrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systemspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMadeira Chemistry Research Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FQUI%2F00674%2F2019/PT
oaire.citation.endPage200013pt_PT
oaire.citation.issue1-2pt_PT
oaire.citation.startPage200013pt_PT
oaire.citation.titleMedicine Researchpt_PT
oaire.citation.volume4pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameOlim
person.familyNameNeves
person.familyNameTomás
person.familyNameSheng
person.givenNameFilipe
person.givenNameAna Rute
person.givenNameHelena
person.givenNameRuilong
person.identifier556975
person.identifierhttps://scholar.google.ca/citations?user=YCheaFsAAAAJ&hl=en
person.identifier.ciencia-id911A-2894-E357
person.identifier.ciencia-idA51A-E760-E8B8
person.identifier.ciencia-id4D14-D31E-A8BE
person.identifier.ciencia-idC019-C809-403B
person.identifier.orcid0000-0001-8878-2067
person.identifier.orcid0000-0003-4262-5837
person.identifier.orcid0000-0002-7856-2041
person.identifier.orcid0000-0002-3303-3832
person.identifier.ridO-6395-2018
person.identifier.ridH-3743-2013
person.identifier.ridE-5991-2010
person.identifier.scopus-author-id56731303900
person.identifier.scopus-author-id6508104177
person.identifier.scopus-author-id7005472737
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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