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- Cyclotriphosphazene-based derivatives for antibacterial Applications: an update on recent advancesPublication . Su, Xiqi; Wang, Le; Xie, JingHua; Liu, XiaoHui; Tomás, HelenaAs a phosphorus scaffold, hexachlorocyclotriphosphazene (HCCP) is widely used for the synthesis of varieties of derivatives, including metal-binding complexes and several unique organometallic compounds, which exhibit potential catalytic, flame retardant and bio logical activities. Some metal-binding HCCP derivatives have shown antibacterial activities as free ligands and metal complexes. These derivatives can also serve as building blocks for the formation of antibacterial metal-containing polymers. This mini-review is focused on the de sign and development of HCCP derivatives as potential antibacterial agents with representa tive examples as well as antibacterial mechanisms from recent years