Cyclotriphosphazene-based derivatives for antibacterial Applications: an update on recent advances

Su, Xiqi; Wang, Le; Xie, JingHua; Liu, XiaoHui; Tomás, Helena

http://hdl.handle.net/10400.13/4331

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Abstract(s)

As a phosphorus scaffold, hexachlorocyclotriphosphazene (HCCP) is widely used for the synthesis of varieties of derivatives, including metal-binding complexes and several unique organometallic compounds, which exhibit potential catalytic, flame retardant and bio logical activities. Some metal-binding HCCP derivatives have shown antibacterial activities as free ligands and metal complexes. These derivatives can also serve as building blocks for the formation of antibacterial metal-containing polymers. This mini-review is focused on the de sign and development of HCCP derivatives as potential antibacterial agents with representa tive examples as well as antibacterial mechanisms from recent years

Keywords

Hexachlorocyclotriphosphazene(HCCP) Antibacterial Antibacterial mechanism Metal Ligand Polymer . Faculdade de Ciências Exatas e da Engenharia Centro de Química da Madeira

URI

http://hdl.handle.net/10400.13/4331

Citation

Su, X., Wang, L., Xie, J., Liu, X., & Tomás, H. (2021). Cyclotriphosphazene-based derivatives for antibacterial applications: an update on recent advances. Current Organic Chemistry, 25(2), 301-314.