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HLA‐A polymorphisms in four ethnic groups from Guinea‐Bissau (West Africa) inferred from sequence‐based typing

dc.contributor.authorSpínola, C.
dc.contributor.authorBruges-Armas, J.
dc.contributor.authorBrehm, A.
dc.contributor.authorSpínola, H.
dc.date.accessioned2018-11-09T16:14:45Z
dc.date.available2018-11-09T16:14:45Z
dc.date.issued2008-08
dc.description.abstractHuman leukocyte antigen (HLA)-A locus polymorphisms were examined at highresolution level, using sequence-based typing, in the four most representative Guinea-Bissau(NorthwestAfrica)ethnicgroups:Balanta,Bijago´ s,FulaandPapel. DespitetheFulagrouphavingsignificantdifferenceswhencomparedwiththeother three ethnic groups, all four groups most likely received a genetic input from non sub-Saharans. The Bijago´ s and Papel groups showed similarities to neighboring populations from Mali and Senegal. The Balanta, despite their oral tradition of an East Africa origin, show affinities to Cameroon populations, highly influenced by Bantu migrations. These results are congruent with historical sources and other genetic studies that support the finding that the Guinea-Bissau genetic pool was influenced by several migrations from North Africa, Sahara and East Africa.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSpínola, C., Bruges‐Armas, J., Brehm, A., & Spinola, H. (2008). HLA‐A polymorphisms in four ethnic groups from Guinea‐Bissau (West Africa) inferred from sequence‐based typing. Tissue Antigens, 72(6), 593-598.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/2152
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.subjectHLA-Apt_PT
dc.subjectSequence-based typingpt_PT
dc.subjectSub-Saharan populationspt_PT
dc.subjectGuinea-Bissaupt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências da Vidapt_PT
dc.titleHLA‐A polymorphisms in four ethnic groups from Guinea‐Bissau (West Africa) inferred from sequence‐based typingpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POCI/POCI%2FBIA-BCM%2F60440%2F2004/PT
oaire.citation.endPage598pt_PT
oaire.citation.startPage593pt_PT
oaire.citation.titleTissue Antigenspt_PT
oaire.citation.volume72(6)pt_PT
oaire.fundingStreamPOCI
person.familyNameArmas
person.familyNameBrehm
person.familyNameSpínola
person.givenNameJacome
person.givenNameAntonio
person.givenNameHélder
person.identifier682991
person.identifier.ciencia-id8413-FBC3-5584
person.identifier.ciencia-id3613-8D1F-0EDF
person.identifier.orcid0000-0001-7671-6521
person.identifier.orcid0000-0003-3168-5340
person.identifier.orcid0000-0002-6455-1595
person.identifier.scopus-author-id55931428200
person.identifier.scopus-author-idAuthor ID 7006085833
person.identifier.scopus-author-id10242534600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication62d279e2-247a-4652-a370-3e8c2a846e31
relation.isAuthorOfPublication1ba0f1f6-73c8-46b2-b152-8cd3c90207ed
relation.isAuthorOfPublication.latestForDiscovery62d279e2-247a-4652-a370-3e8c2a846e31
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