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Electrospun polylactic acid-chitosan composite: a bio-based alternative for inorganic composites for advanced application

2018Journal article Open access
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dc.contributor.authorThomas, Merin Sara
dc.contributor.authorPillai, Prasanth K. S.
dc.contributor.authorFaria, Marisa
dc.contributor.authorCordeiro, Nereida
dc.contributor.authorBarud, Hernane
dc.contributor.authorThomas, Sabu
dc.contributor.authorPothen, Laly A.
dc.date.accessioned2021-04-22T15:12:37Z
dc.date.available2021-04-22T15:12:37Z
dc.date.issued2018
dc.description.abstractFabricating novel materials for biomedical applications mostly require the use of biodegradable materials. In this work biodegradable materials like polylactic acid (PLA) and chitosan (CHS) were used for designing electrospun mats. This work reports the physical and chemical characterization of the PLA-CHS composite, prepared by the electrospinning technique using a mixed solvent system. The addition of chitosan into PLA, offered decrease in fiber diameter in the composites with uniformity in the distribution of fibers with an optimum at 0.4wt% CHS. The fiber formation and the reduction in fiber diameter were confirmed by the SEM micrograph. The inverse gas chromatography and contact angle measurements supported the increase of hydrophobicity of the composite membrane with increase of filler concentration. The weak interaction between PLA and chitosan was confirmed by Fourier transform infrared spectroscopy and thermal analysis. The stability of the composite was established by zeta potential measurements. Cytotoxicity studies of the membranes were also carried out and found that up to 0.6% CHS the composite material was noncytotoxic. The current findings are very important for the design and development of new materials based on polylactic acid-chitosan composites for environmental and biomedical applications.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationThomas, M. S., Pillai, P. K., Faria, M., Cordeiro, N., Barud, H., Thomas, S., & Pothen, L. A. (2018). Electrospun polylactic acid-chitosan composite: a bio-based alternative for inorganic composites for advanced application. Journal of Materials Science: Materials in Medicine, 29(9), 1-12.pt_PT
dc.identifier.doi10.1007/s10856-018-6146-1pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/3316
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectElectrospun polylactic acid-chitosan compositept_PT
dc.subjectInorganic composites for advanced applicationpt_PT
dc.subjectPLA-CHS compositept_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.titleElectrospun polylactic acid-chitosan composite: a bio-based alternative for inorganic composites for advanced applicationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue9pt_PT
oaire.citation.startPage137pt_PT
oaire.citation.titleJournal of Materials Science: Materials in Medicinept_PT
oaire.citation.volume29pt_PT
person.familyNameFaria
person.familyNamecordeiro
person.givenNameMarisa Camacho Gonçalves
person.givenNamenereida
person.identifier1612636
person.identifier.ciencia-idD716-6F48-AD0E
person.identifier.ciencia-id521A-0F62-EA39
person.identifier.orcid0000-0002-9158-6961
person.identifier.orcid0000-0001-6006-3415
person.identifier.ridO-2253-2019
person.identifier.scopus-author-id7004319456
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication57ef72f0-8e40-4853-b4ab-416884e127fa
relation.isAuthorOfPublication3d02b657-c48c-4f56-813a-1284b81960f3
relation.isAuthorOfPublication.latestForDiscovery57ef72f0-8e40-4853-b4ab-416884e127fa

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