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Study on the cyclization of 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine: microwave versus thermal preparation of pyrido[4,3-d]pyrimidines

2009Journal article Open access
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dc.contributor.authorCikotiene, Inga
dc.contributor.authorKairys, Visvaldas
dc.contributor.authorBuksnaitiene, Rita
dc.contributor.authorMorkunas, Marius
dc.contributor.authorRudys, Simonas
dc.contributor.authorBrukstus, Algirdas
dc.contributor.authorFernandes, Miguel X.
dc.date.accessioned2023-02-07T14:43:56Z
dc.date.available2023-02-07T14:43:56Z
dc.date.issued2009
dc.description.abstractThermal and microwave initiated cyclization of 2,4-disubstituted 6-arylethynylpyrimidine-5-carbalde hydes with tert-butylamine has been studied. A novel high-yielding preparation of 2,4-disubstituted 7- arylpyrido[4,3-d]pyrimidines has been developed. The intermediate compounds were isolated and possible mechanism of the reactions is discussed.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCikotiene, I., Kairys, V., Buksnaitiene, R., Morkunas, M., Rudys, S., Brukstus, A., & Fernandes, M. X. (2009). Study on the cyclization of 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine: microwave versus thermal preparation of pyrido [4, 3-d] pyrimidines. Tetrahedron, 65(29-30), 5752-5759.pt_PT
dc.identifier.doi10.1016/j.tet.2009.05.015pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/5010
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationCOMPUTATIONAL MODELING OF PHOSPHODIESTERASE 3 INHIBITORS
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectCyclizationpt_PT
dc.subjectMicrowavept_PT
dc.subject6-Arylethynylpyrimidine-5-carbaldehydespt_PT
dc.subjectPyrido[4,3-d]pyrimidinespt_PT
dc.subject1,6-Electrocyclic reactionpt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.titleStudy on the cyclization of 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine: microwave versus thermal preparation of pyrido[4,3-d]pyrimidinespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleCOMPUTATIONAL MODELING OF PHOSPHODIESTERASE 3 INHIBITORS
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/PIDDAC/SFRH%2FBPD%2F41787%2F2007/PT
oaire.citation.endPage5759pt_PT
oaire.citation.issue29-30pt_PT
oaire.citation.startPage5752pt_PT
oaire.citation.titleTetrahedronpt_PT
oaire.citation.volume65pt_PT
oaire.fundingStreamPIDDAC
person.familyNameKairys
person.familyNameFernandes
person.givenNameVisvaldas
person.givenNameMiguel Xavier
person.identifierK-9893-2013
person.identifier.ciencia-idA716-F916-AFB2
person.identifier.ciencia-idED1D-3C7A-467C
person.identifier.orcid0000-0002-5427-0175
person.identifier.orcid0000-0002-1840-616X
person.identifier.ridA-4373-2013
person.identifier.scopus-author-id6602925161
person.identifier.scopus-author-id35466972500
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication43821a45-10cf-4dbd-bc5a-fa88d146fc36
relation.isAuthorOfPublication8dab9a0d-f44a-4d2d-b9b1-7b3145162ca3
relation.isAuthorOfPublication.latestForDiscovery8dab9a0d-f44a-4d2d-b9b1-7b3145162ca3
relation.isProjectOfPublication83f5bc83-bb92-4694-86ca-d205d250f2da
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