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A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells

dc.contributor.authorZhu, Beitong
dc.contributor.authorWu, Xiaoli
dc.contributor.authorRodrigues, João
dc.contributor.authorHu, Xichao
dc.contributor.authorSheng, Ruilong
dc.contributor.authorBao, Guang-Ming
dc.date.accessioned2022-02-17T10:59:42Z
dc.date.available2022-02-17T10:59:42Z
dc.date.issued2021
dc.description.abstractHydrazine (N2H4) and ClO− are very harmful for public health, hence it is important and necessary to monitor them in living cells. Herein, we rationally designed and synthesized a dual-analytes responsive fluorescent sensor PTMQ for distinguishing detection of N2H4 and ClO−. PTMQ underwent N2H4-induced double bond cleavage, affording colorimetric and green fluorescence enhancement with good selectivity and a low detection limit (89 nM). On the other hand, PTMQ underwent ClO−-induced sulfur oxidation and displayed red fluorescence lighting-up response towards ClO− with good selectivity, rapid response (<0.2 min) and a low detection limit (58 nM). Moreover, PTMQ was successfully employed for in-situ imaging of N2H4 and ClO− in living cellspt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationZhu, B., Wu, X., Rodrigues, J., Hu, X., Sheng, R., & Bao, G. M. (2021). A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 246, 118953. https://doi.org/10.1016/j.saa.2020.118953pt_PT
dc.identifier.doi10.1016/j.saa.2020.118953pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/4088
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationMadeira Chemistry Research Centre
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectFluorescent probept_PT
dc.subjectDual-analytespt_PT
dc.subjectN2H4pt_PT
dc.subjectClO−pt_PT
dc.subjectBioimagingpt_PT
dc.subjectLiving cellspt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.subjectCentro de Química da Madeira
dc.titleA dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cellspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMadeira Chemistry Research Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00674%2F2020/PT
oaire.citation.startPage118953pt_PT
oaire.citation.titleSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopypt_PT
oaire.citation.volume246pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameRodrigues
person.familyNameSheng
person.givenNameJoão
person.givenNameRuilong
person.identifierhttps://scholar.google.ca/citations?user=YCheaFsAAAAJ&hl=en
person.identifier.ciencia-idA81C-620E-DD6A
person.identifier.ciencia-idC019-C809-403B
person.identifier.orcid0000-0003-4552-1953
person.identifier.orcid0000-0002-3303-3832
person.identifier.ridB-6816-2008
person.identifier.scopus-author-id9233278800
person.identifier.scopus-author-id7005472737
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication53031fca-b2e7-4ce4-bda9-61e486da4547
relation.isAuthorOfPublication447440d5-343e-4804-a4fb-98584bb0749c
relation.isAuthorOfPublication.latestForDiscovery447440d5-343e-4804-a4fb-98584bb0749c
relation.isProjectOfPublicatione30e13d9-be9a-4f34-91ea-a1682abce74e
relation.isProjectOfPublication.latestForDiscoverye30e13d9-be9a-4f34-91ea-a1682abce74e

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