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Laponite®: a key nanoplatform for biomedical applications?

2018Journal article Restricted access
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dc.contributor.authorTomás, Helena
dc.contributor.authorAlves, Carla S.
dc.contributor.authorRodrigues, João
dc.date.accessioned2019-06-27T14:06:08Z
dc.date.available2019-06-27T14:06:08Z
dc.date.issued2018
dc.description.abstractLaponite® is a synthetic smectite clay that already has many important technological applications, which go beyond the conventional uses of clays in pharmaceutics and cosmetics. In biomedical applications, particularly in nanomedicine, this material holds great potential. Laponite® is a 2-dimensional (2D) nanomaterial composed of disk-shaped nanoscale crystals that have a high aspect ratio. These disks can strongly interact with many types of chemical entities (from small molecules or ions, to natural or synthetic polymers, to different inorganic nanoparticles) and are also easily functionalized and readily degraded in the physiological environment giving rise to non-toxic and even bioactive products. This review will highlight the potential of Laponite® as a nanomaterial in the fields of drug delivery, bioimaging, tissue engineering and regenerative medicine. New concepts, as well as novel innovative materials that stand out from the usual ones due to the unique properties of Laponite®, will also be presented and discussed.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTomás, H., Alves, C. S., & Rodrigues, J. (2018). Laponite®: a key nanoplatform for biomedical applications?. Nanomedicine: Nanotechnology, Biology and Medicine, 14(7), 2407-2420.pt_PT
dc.identifier.doi10.1016/j.nano.2017.04.016pt_PT
dc.identifier.issn1549-9634
dc.identifier.urihttp://hdl.handle.net/10400.13/2437
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationStrategic Project - UI 674 - 2014
dc.subjectLaponitept_PT
dc.subjectNanomedicinept_PT
dc.subjectDrug deliverypt_PT
dc.subjectBioimagingpt_PT
dc.subjectTissue engineeringpt_PT
dc.subjectRegenerative medicinept_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.subjectCentro de Química da Madeira
dc.titleLaponite®: a key nanoplatform for biomedical applications?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 674 - 2014
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FQUI%2FUI0674%2F2014/PT
oaire.citation.endPage2420pt_PT
oaire.citation.startPage2407pt_PT
oaire.citation.titleNanomedicine: Nanotechnology, Biology and Medicinept_PT
oaire.citation.volume14(7)pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameTomás
person.familyNameAlves
person.familyNameRodrigues
person.givenNameHelena
person.givenNameCarla Sophia
person.givenNameJoão
person.identifier556975
person.identifier.ciencia-id4D14-D31E-A8BE
person.identifier.ciencia-idA81C-620E-DD6A
person.identifier.orcid0000-0002-7856-2041
person.identifier.orcid0000-0002-8891-5234
person.identifier.orcid0000-0003-4552-1953
person.identifier.ridE-5991-2010
person.identifier.ridB-6816-2008
person.identifier.scopus-author-id6508104177
person.identifier.scopus-author-id11438813200
person.identifier.scopus-author-id9233278800
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication3a747114-6ab9-454b-985b-00cbf792e273
relation.isAuthorOfPublicationa94320e0-abf7-4fcb-a607-966133a78f3e
relation.isAuthorOfPublication53031fca-b2e7-4ce4-bda9-61e486da4547
relation.isAuthorOfPublication.latestForDiscovery53031fca-b2e7-4ce4-bda9-61e486da4547
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