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Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health

2017Journal article Open access
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dc.contributor.authorMelo, Xavier
dc.contributor.authorSantos, Diana A.
dc.contributor.authorOrnelas, Rui
dc.contributor.authorFernhall, Bo
dc.contributor.authorSanta-Clara, Helena
dc.contributor.authorSardinha, Luís B.
dc.date.accessioned2021-11-18T14:28:12Z
dc.date.available2021-11-18T14:28:12Z
dc.date.issued2017
dc.description.abstractPurpose: We examined whether exposure to high PP in adolescence predicts carotid artery intima-media thickness (IMT) and stiffness indices at young adulthood. Methods: Seventy-nine participants had their brachial systolic (SBP) and diastolic blood (DBP) pressures taken at the age of 15–16 years and later at young adulthood (29–31 years). Carotid IMT, distensibility and stiffness index b were measured at young adulthood. Linear and logistical regression analysis were performed. Results: PP at adolescence and at young adulthood predicted vascular health independently of sex, body mass index, and mean arterial pressure, explaining up to 37% of the variance. When analyzing its single constituents, at adolescence DBP was more predictive of vascular health, whereas DBP and SBP were equally important at young adulthood. Adolescents with high PP were at risk for increased carotid IMT (OR: 4.04–4.09), even if PP decreased at young adulthood. Young adults with high PP were at risk for increased stiffness regardless of adolescence PP (OR: 4.64–7.35). Conclusion: PP at adolescence and young adulthood may be a better predictor of early pathological changes in carotid artery structure and stiffness. Whereas carotid IMT in young adults appears to be influenced by PP at adolescence, carotid stiffness depends primarily on current PP.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMelo, X., Santos, D. A., Ornelas, R., Fernhall, B., Santa-Clara, H., & Sardinha, L. B. (2018). Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health. Blood pressure, 27(1), 19-24. https://doi.org/10.1080/08037051.2017.1360724 Melo, X., Santos, D. A., Ornelas, R., Fernhall, B., Santa-Clara, H., & Sardinha, L. B. (2018). Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health. Blood pressure, 27(1), 19-24. https://doi.org/10.1080/08037051.2017.13607pt_PT
dc.identifier.doi10.1080/08037051.2017.1360724pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/3833
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherEuropean Society of Hypertension (ESH)pt_PT
dc.relationPhysical activity, cardiorespiratory fitness and body composition during childhood and adolescence as determinants of metabolic risk and arterial properties in young adulthood: secular trends, developmental trajectories and genetic interactions
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAtherosclerosispt_PT
dc.subjectarteriosclerosispt_PT
dc.subjectBlood pressurept_PT
dc.subjectIntima media thicknesspt_PT
dc.subjectArterial stiffnesspt_PT
dc.subjectEpidemiologypt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Sociaispt_PT
dc.titlePulse pressure tracking from adolescence to young adulthood: contributions to vascular healthpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitlePhysical activity, cardiorespiratory fitness and body composition during childhood and adolescence as determinants of metabolic risk and arterial properties in young adulthood: secular trends, developmental trajectories and genetic interactions
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FDES%2F119028%2F2010/PT
oaire.citation.endPage24pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage19pt_PT
oaire.citation.titleBlood Pressurept_PT
oaire.citation.volume27pt_PT
oaire.fundingStream3599-PPCDT
person.familyNameMelo
person.familyNameOrnelas
person.familyNameFernhall
person.familyNameSardinha
person.givenNameXavier
person.givenNameRui
person.givenNameBo
person.givenNameLuis
person.identifierZhUtetAAAAAJ&hl
person.identifier.ciencia-idD010-C9C5-5147
person.identifier.ciencia-idA71A-D19E-55F4
person.identifier.ciencia-idA812-2D8E-1BC9
person.identifier.orcid0000-0003-3934-3986
person.identifier.orcid0000-0003-3737-7402
person.identifier.orcid0000-0001-9393-3018
person.identifier.orcid0000-0002-6230-6027
person.identifier.scopus-author-id36613303700
person.identifier.scopus-author-id24335790700
person.identifier.scopus-author-id6603814844
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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