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Injectable hybrid laponite/alginate hydrogels for sustained release of methylene blue

2011Journal article Restricted access
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dc.contributor.authorLi, Yulin
dc.contributor.authorSantos, José Luís
dc.contributor.authorMaciel, Dina
dc.contributor.authorTomás, Helena
dc.contributor.authorRodrigues, João
dc.date.accessioned2019-06-18T13:21:01Z
dc.date.available2019-06-18T13:21:01Z
dc.date.issued2011
dc.description.abstractThe incorporation of biocompatible Laponite (LP) into alginate hydrogels greatly increases the drug encapsulation efficiency of methylene blue (MB). By raising the LP content from 0 to 0.5 wt.%, the half-release time (t1/2) of MB in oven-dried gels increases from ~2 h to ~10 h, while t1/2 in vacuum-dried gels slightly changes from ~1 h to ~2 h. Increasing LP content together with drying modes can induce the MB release mechanism froma diffusion-controlled release into a swelling-controlled one.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationLi, Y., Santos, J. L., Maciel, D., Tomás, H., & Rodrigues, J. (2011). Injectable hybrid laponite/alginate hydrogels for sustained release of methylene blue. Journal of Controlled Release, 152, e55-e57.pt_PT
dc.identifier.doi10.1016/j.jconrel.2011.08.119pt_PT
dc.identifier.issn0168-3659
dc.identifier.urihttp://hdl.handle.net/10400.13/2405
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectLaponitept_PT
dc.subjectAlginatept_PT
dc.subjectInjectable hybrid hydrogelspt_PT
dc.subjectDrug deliverypt_PT
dc.subjectRelease mechanismpt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.titleInjectable hybrid laponite/alginate hydrogels for sustained release of methylene bluept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPagee57pt_PT
oaire.citation.startPagee55pt_PT
oaire.citation.titleJournal of Controlled Releasept_PT
oaire.citation.volume152pt_PT
person.familyNameLi
person.familyNameMaciel
person.familyNameTomás
person.familyNameRodrigues
person.givenNameYulin
person.givenNameDina
person.givenNameHelena
person.givenNameJoão
person.identifier556975
person.identifier.ciencia-id211C-6048-FB1A
person.identifier.ciencia-id4D14-D31E-A8BE
person.identifier.ciencia-idA81C-620E-DD6A
person.identifier.orcid0000-0001-5569-1038
person.identifier.orcid0000-0001-8684-6100
person.identifier.orcid0000-0002-7856-2041
person.identifier.orcid0000-0003-4552-1953
person.identifier.ridA-4082-2013
person.identifier.ridE-5991-2010
person.identifier.ridB-6816-2008
person.identifier.scopus-author-id55718977200
person.identifier.scopus-author-id54781586200
person.identifier.scopus-author-id6508104177
person.identifier.scopus-author-id9233278800
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationde21a0a9-a5a2-4521-b0e4-5902704f9bb0
relation.isAuthorOfPublication3ad1361c-0475-4b7f-a866-bcb1c2fe9af0
relation.isAuthorOfPublication3a747114-6ab9-454b-985b-00cbf792e273
relation.isAuthorOfPublication53031fca-b2e7-4ce4-bda9-61e486da4547
relation.isAuthorOfPublication.latestForDiscovery53031fca-b2e7-4ce4-bda9-61e486da4547

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