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Publicação
Morpholino-functionalized phosphorus dendrimers for precision regenerative medicine: osteogenic differentiation of mesenchymal stem cells
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Orientador(es)
Resumo(s)
A novel bioactive macromolecule based on morpholino-functiona lized phosphorus dendrimers (generation 2, G2-Mor+
) was devel oped for osteogenic differentiation of mesenchymal stem cells
(MSCs). Interestingly, through in vitro tests, it was shown that G2-
Mor+ dendrimer can strongly promote the transformation of MSCs
into osteoblasts, which implies the potential application of phos phorus de medicine.
Descrição
Palavras-chave
Morpholino-functionalized phosphorus dendrimers Precision regenerative medicine Osteogenic differentiation Mesenchymal stem cells . Faculdade de Ciências Exatas e da Engenharia Centro de Química da Madeira
Contexto Educativo
Citação
Li, A., Fan, Y., Cao, X., Chen, L., Wang, L., Alves, C. S., ... & Shi, X. (2019). Morpholino-functionalized phosphorus dendrimers for precision regenerative medicine: osteogenic differentiation of mesenchymal stem cells. Nanoscale, 11(37), 17230-17234. DOI: 10.1039/C9NR06410A
Editora
Royal Society of Chemistry