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Dendrimers in combination with natural products and analogues as anti-cancer agents

2018-01-22Journal article Restricted access
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dc.contributor.authorMignani, Serge
dc.contributor.authorRodrigues, João
dc.contributor.authorTomás, Helena
dc.contributor.authorZablocka, Maria
dc.contributor.authorShi, Xiangyang
dc.contributor.authorCaminade, Anne-marie
dc.contributor.authorMajoral, Jean-Pierre
dc.date.accessioned2019-06-27T10:35:33Z
dc.date.available2019-06-27T10:35:33Z
dc.date.issued2018-01-22
dc.description.abstractFor the first time, an overview of dendrimers in combination with natural products and analogues as anti-cancer agents is presented. This reflects the development of drug delivery systems, such as dendrimers, to tackle cancers. The most significant advantages of using dendrimers in nanomedicine are their high biocompatibility, good water solubility, and their entry - with or without encapsulated, complexed or conjugated drugs - through an endocytosis process. This strategy has accelerated over the years in order to develop nanosystems as nanocarriers, to decrease the intrinsic toxicity of anti-cancer agents, to decrease the drug side effects, to increase the efficacy of the treatment, and consequently to improve patient compliance.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMignani, S., Rodrigues, J., Tomas, H., Zablocka, M., Shi, X., Caminade, A. M., & Majoral, J. P. (2018). Dendrimers in combination with natural products and analogues as anti-cancer agents. Chemical Society Reviews, 47(2), 514-532.pt_PT
dc.identifier.doi10.1039/c7cs00550dpt_PT
dc.identifier.issn0306-0012
dc.identifier.urihttp://hdl.handle.net/10400.13/2434
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherRoyal Society of Chemistrypt_PT
dc.relationMadeira Chemistry Research Centre
dc.subjectDendrimerspt_PT
dc.subjectDrug carrierspt_PT
dc.subjectDrug delivery systemspt_PT
dc.subjectNatural productspt_PT
dc.subjectNanomedicinept_PT
dc.subjectNeoplasmspt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.subjectCentro de Química da Madeira
dc.titleDendrimers in combination with natural products and analogues as anti-cancer agentspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMadeira Chemistry Research Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FQUI%2F00674%2F2013/PT
oaire.citation.endPage532pt_PT
oaire.citation.startPage514pt_PT
oaire.citation.titleChemical Society Reviewspt_PT
oaire.citation.volume47(2)pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMignani
person.familyNameRodrigues
person.familyNameTomás
person.familyNameShi
person.familyNameCaminade
person.givenNameSerge
person.givenNameJoão
person.givenNameHelena
person.givenNameXiangyang
person.givenNameAnne-marie
person.identifier556975
person.identifier.ciencia-id8018-B5D2-6983
person.identifier.ciencia-idA81C-620E-DD6A
person.identifier.ciencia-id4D14-D31E-A8BE
person.identifier.ciencia-idBA11-1437-B948
person.identifier.orcid0000-0002-1383-5256
person.identifier.orcid0000-0003-4552-1953
person.identifier.orcid0000-0002-7856-2041
person.identifier.orcid0000-0001-6785-6645
person.identifier.orcid0000-0001-8487-3578
person.identifier.ridB-6816-2008
person.identifier.ridE-5991-2010
person.identifier.ridA-1289-2007
person.identifier.ridE-2819-2015
person.identifier.scopus-author-id7003374430
person.identifier.scopus-author-id9233278800
person.identifier.scopus-author-id6508104177
person.identifier.scopus-author-id7402953116
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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