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Poly(alkylidenamines) dendrimers as scaffolds for the preparation of low-generation ruthenium based metallodendrimers

2011Journal article Restricted access
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dc.contributor.authorRodrigues, João
dc.contributor.authorJardim, Manuel G.
dc.contributor.authorFigueira, João
dc.contributor.authorGouveia, Marisol
dc.contributor.authorTomás, Helena
dc.contributor.authorRissanen, Kari
dc.date.accessioned2019-06-18T10:46:25Z
dc.date.available2019-06-18T10:46:25Z
dc.date.issued2011
dc.description.abstractThe aim of this article is to highlight the use of nitrile-functionalized poly(alkylidenamines) dendrimers as building blocks for the preparation of low-generation ruthenium based cationic metallodendrimers having in view potential biomedical applications. Air-stable poly(alkylidenamines) nitrile dendrimers, peripherally functionalized with the ruthenium moieties [Ru(Z5-C5H5)(PPh3)2]+ or [RuCl(dppe)2]+, have been prepared, characterized and are being studied for their anticancer activity. The followed strategy is based on the biological advantages associated with low-generation dendrimers, the known activity of ruthenium compounds as anticancer drugs and the stability of these dendrimers at the physiological temperature.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRodrigues, J., Jardim, M. G., Figueira, J., Gouveia, M., Tomas, H., & Rissanen, K. (2011). Poly (alkylidenamines) dendrimers as scaffolds for the preparation of low-generation ruthenium based metallodendrimers. New Journal of Chemistry, 35(10), 1938-1943.pt_PT
dc.identifier.doi10.1039/c1nj20364apt_PT
dc.identifier.issn1144-0546
dc.identifier.urihttp://hdl.handle.net/10400.13/2403
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherRoyal Society of Chemistrypt_PT
dc.subjectPoly(alkylidenamines) dendrimerspt_PT
dc.subjectPreparation of low-generation rutheniumpt_PT
dc.subjectLow-generation rutheniumpt_PT
dc.subjectRutheniumpt_PT
dc.subjectMetallodendrimerspt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Exatas e da Engenhariapt_PT
dc.subjectCentro de Química da Madeira
dc.titlePoly(alkylidenamines) dendrimers as scaffolds for the preparation of low-generation ruthenium based metallodendrimerspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FQUI%2F64202%2F2006/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FCTM%2F098451%2F2008/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F29325%2F2006/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F65036%2F2009/PT
oaire.citation.endPage1943pt_PT
oaire.citation.startPage1938pt_PT
oaire.citation.titleNew Journal of Chemistrypt_PT
oaire.citation.volume35pt_PT
oaire.fundingStream3599-PPCDT
oaire.fundingStream3599-PPCDT
oaire.fundingStreamSFRH
oaire.fundingStreamSFRH
person.familyNameRodrigues
person.familyNameFigueira
person.familyNameGouveia
person.familyNameTomás
person.familyNameRissanen
person.givenNameJoão
person.givenNameJoão
person.givenNameMarisol
person.givenNameHelena
person.givenNameKari
person.identifier556975
person.identifier.ciencia-idA81C-620E-DD6A
person.identifier.ciencia-id4D14-D31E-A8BE
person.identifier.orcid0000-0003-4552-1953
person.identifier.orcid0000-0001-8819-2278
person.identifier.orcid0000-0002-6489-5283
person.identifier.orcid0000-0002-7856-2041
person.identifier.orcid0000-0002-7282-8419
person.identifier.ridB-6816-2008
person.identifier.ridA-3631-2013
person.identifier.ridE-5991-2010
person.identifier.scopus-author-id9233278800
person.identifier.scopus-author-id53864978400
person.identifier.scopus-author-id6508104177
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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