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High-density lipoprotein cholesterol level relates to working memory, immediate and delayed cued recall in brazilian older adults: the role of cognitive reserve

2017Journal article Restricted access
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dc.contributor.authorIhle, Andreas
dc.contributor.authorGouveia, Élvio R.
dc.contributor.authorGouveia, Bruna R.
dc.contributor.authorFreitas, Duarte L.
dc.contributor.authorJurema, Jefferson
dc.contributor.authorTinôco, Maria A.
dc.contributor.authorKliegel, Matthias
dc.date.accessioned2018-11-20T16:15:40Z
dc.date.available2018-11-20T16:15:40Z
dc.date.issued2017
dc.description.abstractAims: The present study set out to investigate the relation of the high-density lipoprotein cholesterol (HDL-C) level to cognitive performance and its interplay with key markers of cognitive reserve in a large sample of older adults. Methods: We assessed tests of working memory, immediate and delayed cued recall in 701 older adults from Amazonas, Brazil. The HDL-C level was derived from fasting blood samples. In addition, we interviewed individuals on their education, past occupation, and cognitive leisure activity. Results: A critically low HDL-C level (<40 mg/dL) was significantly related to lower performance in working memory, immediate and delayed cued recall. Moderation analyses suggested that the relations of the HDL-C level to working memory and delayed cued recall were negligible in individuals with longer education, a higher cognitive level of the job, and greater engagement in cognitive leisure activity. Conclusion: Cognitive reserve accumulated during the life course may reduce the detrimental influences of a critically low HDL-C level on cognitive functioning in old age.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationIhle, A., Gouveia, É. R., Gouveia, B. R., Freitas, D. L., Jurema, J., Tinôco, M. A., & Kliegel, M. (2017). High-density lipoprotein cholesterol level relates to working memory, immediate and delayed cued recall in brazilian older adults: the role of cognitive reserve. Dementia and geriatric cognitive disorders, 44(1-2), 84-91.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.13/2178
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKargers Publisherspt_PT
dc.subjectHigh-density lipoprotein cholesterol levelpt_PT
dc.subjectCognitive functioningpt_PT
dc.subjectCognitive reservept_PT
dc.subjectEducationpt_PT
dc.subjectCognitive level of jobpt_PT
dc.subjectCognitive leisure activitypt_PT
dc.subjectOlder adultspt_PT
dc.subjectLife coursept_PT
dc.subjectBrasilpt_PT
dc.subject.pt_PT
dc.subjectFaculdade de Ciências Sociaispt_PT
dc.titleHigh-density lipoprotein cholesterol level relates to working memory, immediate and delayed cued recall in brazilian older adults: the role of cognitive reservept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage91pt_PT
oaire.citation.startPage84pt_PT
oaire.citation.titleDementia and Geriatric Cognitive Disorderspt_PT
oaire.citation.volume44(1-2)pt_PT
person.familyNameIhle
person.familyNameGouveia
person.familyNameGouveia
person.familyNameFreitas
person.familyNameJurema
person.familyNameKliegel
person.givenNameAndreas
person.givenNameÉlvio Rúbio
person.givenNameBruna
person.givenNameDuarte
person.givenNameJefferson
person.givenNameMatthias
person.identifier.ciencia-id3B10-8BDF-0D67
person.identifier.ciencia-idE212-42B7-575E
person.identifier.ciencia-idAA13-1821-A447
person.identifier.ciencia-idA81F-6BDE-2E54
person.identifier.orcid0000-0001-9845-5190
person.identifier.orcid0000-0003-0927-692X
person.identifier.orcid0000-0001-7706-190X
person.identifier.orcid0000-0001-6642-3370
person.identifier.orcid0000-0002-2369-4557
person.identifier.orcid0000-0002-2001-2522
person.identifier.ridB-3793-2016
person.identifier.scopus-author-id56090521600
person.identifier.scopus-author-id37096975400
person.identifier.scopus-author-id6603740686
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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